South Carolina's Biggest Cities

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South Carolina boasts a diverse array of urban centers that showcase the state’s rich cultural landscape and dynamic growth. From historic coastal cities to vibrant inland metropolitan areas, the state’s largest municipalities offer unique characteristics that make them standout destinations for residents and visitors alike.

Top Largest Cities in South Carolina

As of 2026, Charleston leads the pack as South Carolina’s largest city, with a population of 160,965 residents. The city’s remarkable growth and historical significance continue to attract new inhabitants and businesses. Following closely behind are several other significant urban centers that contribute to the state’s economic and cultural vitality.

Population Rankings of Major Cities

Rank City 2026 Population Annual Growth Rate
1 Charleston 160,965 1.04%
2 Columbia 149,078 1.46%
3 North Charleston 131,201 2.02%
4 Mount Pleasant 97,780 1.13%
5 Rock Hill 76,370 0.38%
6 Greenville 75,842 0.98%

Characteristics of South Carolina’s Urban Centers

Each of South Carolina’s major cities brings something unique to the state’s urban landscape. Charleston, known as “The Holy City,” offers a blend of historic charm and modern amenities. As the state’s largest city, it serves as a major cultural and economic hub, attracting tourists and businesses alike.

State Capital Dynamics

Columbia, the state capital, ranks second in population and plays a crucial role in South Carolina’s governance. The city follows a mayor-council government structure, with the mayor serving as the chief executive and the city council providing legislative oversight.

Coastal and Inland Diversity

The state’s largest cities showcase a remarkable diversity in geographical settings. Coastal cities like Charleston and Mount Pleasant offer maritime charm, while inland cities such as Columbia and Greenville provide different urban experiences with their unique cultural and economic landscapes.

Urban Growth and Development

South Carolina’s cities are experiencing steady growth, with most major urban centers showing positive population trends. North Charleston stands out with the highest annual growth rate of 2.02%, indicating the region’s increasing attractiveness for residents and businesses.

The state's municipal structure is diverse, with cities and towns managed through various governance models, including mayor-council and council-manager systems. This flexibility allows each municipality to adapt to its specific community needs and economic challenges.

What is the largest city in South Carolina?

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Charleston is the largest city in South Carolina, with a population of 160,965 as of 2026.

How fast are South Carolina's cities growing?

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Most major cities in South Carolina are experiencing steady growth, with annual rates ranging from 0.38% to 2.02%. North Charleston has the highest growth rate at 2.02%.

What makes South Carolina's cities unique?

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South Carolina's cities offer diverse experiences, from historic coastal towns like Charleston to inland economic centers like Columbia and Greenville, each with its own distinct character and opportunities.